Assessment of vitamin d receptors allelic variation

Details Assessment of vitamin d receptors allelic variation Assessment of vitamin d receptors allelic variation

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C07H 21/04 (2006.01) C07K 14/705 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2141300

The present invention provides a genetic test for assaying predisposition to and/or resistance to high rates of bone turn-over, development of low bone mass and responsiveness or otherwise to therapeutic modalities. This is a specific model for use in prediction of osteoporosis and likely response to preventive or therapeutic modalities. It is a general model of allelic variation in transcriptional regulators determining physiological set-points and thus susceptibility or resistance to certain pathophysiological states.

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