Association between ferroquine and an artemisinine...

A - Human Necessities – 61 – K

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Details

A61K 31/357 (2006.01) A61K 31/4706 (2006.01) A61K 33/26 (2006.01) A61P 33/06 (2006.01)

Patent

CA 2605385

The invention concerns a combination comprising ferroquine, in free base, salt, hydrate or solvate form, and an artemisinine derivative. The invention also concerns a pharmaceutical composition comprising ferroquine, in the form of one of its pharmaceutically acceptable salts, ferroquine hydrate or solvate, and at least one artemisinine derivative. The invention further concerns the use of such a combination for preparing a medicine for treating or preventing malaria. Finally, the invention concerns a kit for treating or preventing malaria.

L'invention a pour objet une association, qui comprend de la ferroquine, sous forme de base libre, de sel, d'hydrate ou de solvat, et un dérivé d'artémisinine. L'invention a également pour objet une composition pharmaceutique comprenant de la ferroquine, sous forme d'un de ses sels pharmaceutiquement acceptables, d'un hydrate ou d'un solvat de la ferroquine, et d'au moins un dérivé d'artémisinine. L'invention a aussi pour objet l'utilisation d'une telle association pour la préparation d'un médicament destiné au traitement ou à la prévention du paludisme. L'invention a enfin pour objet un kit pour le traitement ou la prévention du paludisme.

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