Association of calpain inhibitors and reactive oxygen...

Details Association of calpain inhibitors and reactive oxygen... Association of calpain inhibitors and reactive oxygen...

A - Human Necessities

61

K

A61K 38/55 (2006.01) A61K 31/05 (2006.01) A61K 31/27 (2006.01) A61K 31/54 (2006.01) A61K 45/06 (2006.01) A61P 25/00 (2006.01) A61P 27/00 (2006.01)

Patent

CA 2428709

The invention concerns a pharmaceutical composition comprising, as active principle, at least a calpain inhibiting substance and at least a substance trapping reactive oxygen species (ROS), and optionally an acceptable pharmaceutical carrier. The invention also concerns a product comprising at least a calpain inhibiting substance and at least a substance trapping reactive oxygen species (ROS), selectively or not, as combination product, the active principle being separate.

La présente invention concerne une composition pharmaceutique comprenant, à titre de principe actif, au moins une substance inhibitrice des calpaïnes et au moins une substance piégeur des formes réactives de l'oxygène (ROS pour "reactive oxygen species"), et éventuellement un support pharmaceutiquement acceptable. L'invention concerne également un produit comprenant au moins une substance inhibitrice de calpaïnes et au moins une substance piégeur de formes réactives de l'oxygèn, de manière sélective ou non, en tant que produit de combinaison, sous forme séparée, de ces principes actifs.

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