Association of pde4d allelic variants with stroke

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01)

Patent

CA 2627230

The present invention provides methods for detecting a predisposition for stroke in individuals by correlating allelic variants of the phosphodiesterase 4D (PDE4D) gene and hypertension status. The invention further contemplates kits and computer program products for detecting PDE4D polymorphisms indicative of a predisposition for stroke correlated with an individual's hypertension status.

La présente invention a pour objet des méthodes pour détecter une prédisposition à un accident cérébrovasculaire chez des individus par corrélation de variantes alléliques du gène de la phosphodiestérase 4D (PDE4D) et un état d'hypertension. En outre, l'invention prévoit des trousses et des produits de programmes informatiques pour détecter des polymorphismes de la PDE4D indicatifs d'une prédisposition à un accident cérébrovasculaire corrélés à l~état d'hypertension d'un individu.

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