Association of the h2 haplotype of the p2y12 receptor with...

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01)

Patent

CA 2502454

The invention relates to an in vitro method for determining the risk of developing thrombosis in a subject, and to an in vitro method for determining sensitivity of a subject toward a thienopyridine therapy. Both methods involve identifying a particular haplotype of the P2Y12 receptor gene.

L'invention concerne un procédé in vitro de détermination du risque de développement de thrombose chez un sujet, et un procédé in vitro de détermination de la sensibilité d'un sujet à une thérapie à la thiénopyridine. Ces deux procédés impliquent l'identification d'un haplotype particulier du gène du récepteur P2Y12.

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