Asthma susceptibility loci located at chromosome 1q31 for...

Details Asthma susceptibility loci located at chromosome 1q31 for... Asthma susceptibility loci located at chromosome 1q31 for...

C - Chemistry, Metallurgy

12

N

C12N 15/113 (2010.01) C07H 21/00 (2006.01) C12Q 1/68 (2006.01) C40B 40/06 (2006.01)

Patent

CA 2724632

Methods and composition are provided for diagnosing pediat.pi.c onset asthma based on the single nucleotide polymorphism on chromosome 1q31 wherein said single nucleotide polymorphism is set forth in Table 2 or Table 6 of the instant invention Method and composition are also provided for treating and preventing asthma or other inflammatory conditions in a patient in need thereof comp.pi.sing administering an effective amount of an at least one inhibitor which reduces the expression of DENND1 B gene product.

L'invention concerne des compositions et des méthodes pour la détection et le traitement de l'asthme.

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