Asymeticl 1,4-dihydropyridine-3,5-dicarboxylic acid esters...

Details Asymeticl 1,4-dihydropyridine-3,5-dicarboxylic acid esters... Asymeticl 1,4-dihydropyridine-3,5-dicarboxylic acid esters...

C - Chemistry, Metallurgy

07

D

260/294.2, 260/2

C07D 211/90 (2006.01) C07D 409/04 (2006.01)

Patent

CA 1242201

ABSTRACT New compounds useful as therapeutical agents and useful as inter- mediates for the preparation of other therapeutically active di- -hydropyridines, which new compounds are of the formula Image I wherein R1 in one or two (the same or different) substituents on the phenyl ring selected from the group consisting of NO2, Cl and lower alkyl; R is -CH3, -CHO or Image , wherein R11 and R12 are same or different, straight or optionally branched lower alkyl or both together are part of 5-7 membered ring, provid- ed that when one of R is -CH3 the other is -CHO or Image wherein R11 and R12 have the meaning given above; processes for the preparation of said compounds; pharmaceu- tical preparations containing said compounds, a method for their therapeutical use and new processes using said compounds as inter- mediates for the preparation of therapeutically active dihydro- -pyridines.

427859

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