Asymmetric catalysis

C - Chemistry – Metallurgy – 07 – C

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260/468.2, 260/5

C07C 67/00 (2006.01) C07C 45/74 (2006.01) C07C 49/217 (2006.01) C07C 51/36 (2006.01) C07C 69/00 (2006.01) C07F 5/02 (2006.01)

Patent

CA 1094095

ABSTRACT OF THE DISCLOSURE Catalytic asymmetric hydrogenation of a compound of the formula Image wherein R represents alkyl having from 1 to 5 carbon atoms and R1 represents alkyl or alkoxy having from 1 to 5 carbon atoms or aryl or aryloxy, in the presence of a homogenous, coordination complex catalyst comprising rhodium, iridium or ruthenium in com- bination with an optically active bis phosphine ligand provides an improved process for producing desired optical enantimorphs of 2-phenylethylamines.

259731

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