Asymmetric halogenated benzophenones and process for their...

C - Chemistry – Metallurgy – 07 – C

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C07C 49/76 (2006.01) C07C 45/46 (2006.01) C07C 45/63 (2006.01) C07C 49/813 (2006.01) C07C 49/84 (2006.01) C07C 205/45 (2006.01) C07C 317/24 (2006.01)

Patent

CA 2110112

Abstract of the Disclosure Compounds of the formula Image (1) in which R1 to R5 are hydrogen, fluorine, chlorine or bromine atoms, at least one of the substituents R1 - R5 not being a hydrogen atom, and R6 to R10 are hydrogen, fluorine, chlorine or bromine atoms, nitro, C1-C4-alkyl or C1-C4-alkoxy groups or optionally substituted phenyl or naphthyl groups, it being possible for up to 3 of the substituents R6 - R10 to be C1-C4-alkyl groups C1- C4- alkoxy groups or said aryl groups and for at most one of the substituents R6 - R10 to be a nitro group, and the number of halogen atoms and nitro groups R6 - R10, minus the number of C1-C4-alkyl, C1-C4-alkoxy and aryl groups R6 - R10, being at least 1 less than the number of halogen atoms R1 to R5, and process for their preparation by acylating appropriate halogenated benzenes with appropriate substituted benzoyl halides in the presence of a catalyst at 0° to 230°C and reacting (fluorinating) the resulting benzophenones, if appropriate at 120°C to 280°C, with KF, RbF or CsF.

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