C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 491/048 (2006.01) C07D 491/04 (2006.01)
Patent
CA 2122511
ABSTRACT OF THE DISCLOSURE A novel process for the asymmetric hydrogenation of a furoimidazole derivative of the general formula: Image I with hydrogen in the presence of a homogeneous catalyst to produce the corresponding diastereomeric dihydrofuroimidazole derivative of the general formula: Image II is described. Dihydrofuroimidazole derivatives of the general formula II are intermediates for the preparation of the vitamin (+)-biotin.
Eyer Martin
Fuchs Rudolf
Mcgarrity John
Spindler Felix
G. Ronald Bell & Associates
Lonza Ltd.
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