Asymmetric membranes for drug delivery devices

Details Asymmetric membranes for drug delivery devices Asymmetric membranes for drug delivery devices

A - Human Necessities

61

K

A61K 9/28 (2006.01) A61K 31/495 (2006.01)

Patent

CA 2650211

The present invention provides an osmotic dosage form comprising a core containing at least one pharmaceutically active ingredient and which also comprises at least one asymmetric membrane coating wherein said coating comprises one or more substantially water-insoluble polymers, and, one or more solid, water-soluble polymeric materials that do not generate significant amounts of hydrogen peroxide or formaldehyde in long term storage.

L'invention concerne une forme de dosage osmotique comprenant un noyau qui contient au moins un ingrédient pharmaceutiquement actif et au moins un revêtement de membrane asymétrique. Ledit revêtement comprend un ou plusieurs polymères sensiblement insolubles dans l'eau et un ou plusieurs matériaux polymères solides solubles dans l'eau qui ne génèrent pas de quantités significatives de peroxyde d'hydrogène ou de formaldéhyde en stockage à long terme.

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