Asymmetric reduction of 1,1,1-trifluoroacetone

C - Chemistry – Metallurgy – 12 – P

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C12P 7/04 (2006.01)

Patent

CA 2614408

The invention relates to a scalable biocatalytic process for the preparation of S- 1,1,1- trifluoro-2-propanol with a enantiomeric excess of > 99 % by asymmetric microbial reduction of 1, 1, 1- trifluoroacetone with Baker's yeast.

L'invention concerne un procédé biocatalytique modulable de préparation of S-1,1,1-trifluoro-2-propanol à excès énantiomérique > 99 %, par réduction microbienne asymétrique de 1,1,1-trifluoroacétone au moyen de levure de boulangerie.

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