C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 213/53 (2006.01) C07C 29/48 (2006.01) C07C 35/28 (2006.01) C07C 45/28 (2006.01) C07C 45/29 (2006.01) C07C 49/433 (2006.01) C07C 49/513 (2006.01) C07C 251/20 (2006.01) C07C 271/12 (2006.01) C07C 317/28 (2006.01) C07C 323/45 (2006.01) C07D 233/64 (2006.01) C07D 271/06 (2006.01) C07D 277/28 (2006.01) C07D 333/22 (2006.01)
Patent
CA 2192417
This invention relates to processes for asymmetrically producing enantiomerically pure .alpha.- cycloalkylalkyl substitututed methanamines from .alpha.-pinene. One key step of the process of this invention utilizes the oxidation product of .alpha.-pinene, hydroxy pinanone, as a chiral auxiliary to direct the stereoselective alkylation of the corresponding ketimine. This invention also relates to key intermediates useful in the processes referred to herein.
Landi John J. Jr.
Roth Gregory P.
Boehringer Ingelheim Pharmaceuticals Inc.
Fetherstonhaugh & Co.
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