Asymmetrical hydrogenation

Details Asymmetrical hydrogenation Asymmetrical hydrogenation

C - Chemistry, Metallurgy

07

C

C07C 29/17 (2006.01) C07C 33/20 (2006.01) C07C 33/34 (2006.01) C07D 211/14 (2006.01) C07D 265/30 (2006.01) C07D 295/03 (2006.01)

Patent

CA 2058112

PF/5-18784/A/ROC 3056 Asymmetrical hydrogenation Abstract of the Disclosure There is disclosed a process for the asymmetrical hydrogenation of (E)-2-methyl-3-phenyl-2-propen-1-ol of formula Image wherein R1 is as defined herein, to give compounds of formula Image The catalyst is a neutral or cationic rhodium complex of an atropisomeric phosphine.

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