Asymmetrically modified boron hydride type compound, a...

C - Chemistry – Metallurgy – 07 – D

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260/313, 260/602

C07D 249/08 (2006.01) C07C 91/22 (1985.01) C07C 103/30 (1985.01)

Patent

CA 1221097

ABSTRACT OF THE DISCLOSURE: The present invention relates to an asymmetrically modified borohydride type compound obtained by reacting an optically active amino alcohol represented by the formula, Image wherein R1 represents an aryl, alkyl, cycloalkyl or aralkyl group, R2 represents an aryl, alkyl, aralkyl or alkoxycarbonyl group, R3 represents a hydrogen atom or an alkyl or aralkyl group, and a mark * means an asymmetric carbon, or its salt with an acid with a borohydride compound; its production method; and a method for producing an optically active alcohol derivative which is useful as fungicides, herbicides or plant growth regulators, represented by the formula, Image wherein R4 represents an alkyl, cycloalkyl or cycloalkenyl group, or a phenyl group which may be substituted with at least one of halogen, alkyl, haloalkyl, cyano, alkoxyl, phenoxy or phenyl, R5 represents an imidazol-1-yl or 1,2,4-triazol-1-yl group, R6 represents a tert-butyl group, or a 1,1-dimethyl-2-phenylethyl group wherein benzene ring may be substituted with at least one of halogen atom, and a mark * has the same meaning as above, by carrying out the asymmetric reduction of a ketone compound represented by the formula, Image wherein R4, R5 and R6 have the same meanings as above, with said asymmetrically modified boron hydride type compound.

455664

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