Atropisomers of 2-purinyl-3-tolyl-quinazolinone derivatives...

Details Atropisomers of 2-purinyl-3-tolyl-quinazolinone derivatives... Atropisomers of 2-purinyl-3-tolyl-quinazolinone derivatives...

C - Chemistry, Metallurgy

07

D

C07D 473/34 (2006.01) A61K 31/52 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2756347

The invention provides compounds, compositions and methods to treat certain inflammatory conditions and/or oncology by administering a compound that inhibits PD K isoforms, particularly the delta isoform. It further provides specific stereoisomers of a compound useful for these methods. In particular, the compound is an optically active atropisomer of 2-((6-amino-9H- purin-9-yl)methyl)-5-methyl-3-o-tolylquinazolin-4(3H)- one.

L'invention concerne des composés, des compositions et des procédés utiles dans le traitement de certains états pathologiques inflammatoires et/ou oncologiques, par l'administration d'un composé qui inhibe des isoformes de PD K, en particulier l'isoforme delta. Elle concerne de plus des stéréo-isomères spécifiques d'un composé utile dans ces procédés. En particulier, ledit composé est un atropisomère optiquement actif du composé 2-((6-amino-9H-purin-9-yl)méthyl)-5-méthyl-3-o-tolylquinazolin-4(3H)-one.

Affiliated with

Also associated with

Rating

Atropisomers of 2-purinyl-3-tolyl-quinazolinone derivatives... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Atropisomers of 2-purinyl-3-tolyl-quinazolinone derivatives..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Atropisomers of 2-purinyl-3-tolyl-quinazolinone derivatives... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1781271