C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 5/10 (2006.01) C07K 14/705 (2006.01) C12N 11/00 (2006.01) C12N 11/02 (2006.01) C12N 15/85 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/566 (2006.01) C12N 5/06 (2006.01)
Patent
CA 2222718
Attachment enhanced human embryonic kidney cells, 293, are provided. These cells have been modified to contain a selected mammalian scavenger gene, which has been found to improve the ability of these cells to attach in culture. The improved cells of the invention are useful in assays in which the unmodified 293 cells could be used.
L'invention concerne des cellules de reins d'embryons humains, les cellules 293, présentant une faculté de fixation améliorée. Ces cellules ont été modifiées de façon à ce qu'elles contiennent un gène de mammifère piège sélectionné, capable d'améliorer la faculté de ces cellules à se fixer dans une culture. Ces cellules améliorées peuvent être utilisées dans des techniques où des cellules 293 non modifiées pourraient être utilisées.
Brawner Mary Ellen
Elshourbagy Nabil Abd Elsalam
Lysko Paul George
Glaxosmithkline Llc
Gowling Lafleur Henderson Llp
Smithkline Beecham Corporation
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