Attachment of second harmonic-active moiety to molecules for...

Details Attachment of second harmonic-active moiety to molecules for... Attachment of second harmonic-active moiety to molecules for...

G - Physics

01

N

G01N 33/58 (2006.01) G01N 33/50 (2006.01) G01N 33/533 (2006.01) G01N 33/542 (2006.01) G01N 33/543 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2431148

This invention provides methods of detecting molecules at an interface, which comprise labeling the molecules with a second harmonic-active moiety and detecting the labeled molecules at the interface using a surface selective technique. The invention also provides methods for detecting a molecule in a medium and for determining the orientation of a molecular species within a planar surface using a second harmonic-active moiety and a surface selective technique.

L'invention concerne des procédés de détection de molécules au niveau d'une interface. Selon ces procédés, il faut étiqueter les molécules grâce à un second groupe fonctionnel harmonique-actif et détecter les molécules étiquetées au niveau de l'interface au moyen d'une technique sélective de surface. L'invention concerne également des procédés de détection dans un support et de détermination de l'orientation d'une espèce moléculaire à l'intérieur d'une surface plane en utilisant un second groupe fonctionnel harmonique-actif et une technique sélective de surface.

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