Attachment of unmodified nucleic acids to silanized solid...

Details Attachment of unmodified nucleic acids to silanized solid... Attachment of unmodified nucleic acids to silanized solid...

C - Chemistry, Metallurgy

12

M

C12M 1/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/00 (2006.01)

Patent

CA 2292896

The invention relates to a simple, cost effective method for immobilizing synthetic nucleic acid molecules onto a solid support. The invention further concerns the use of such immobilized molecules in nucleic acid hybridization assays, sequencing by hybridization assays, and genetic analyses and combinatorial analyses involving nucleic acids or proteins for screening applications.

L'invention concerne un procédé, simple et rentable, d'immobilisation de molécules d'acides nucléiques synthétiques sur un support solide. L'invention concerne également l'utilisation de ces molécules immobilisées dans des analyses d'hybridation d'acides nucléiques, dans le séquençage par analyses d'hybridation, et dans les analyses génétiques et combinatoires impliquant des acides nucléiques ou des protéines pour des applications de criblage.

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