A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/12 (2006.01) A61P 31/14 (2006.01) C12N 7/08 (2006.01) C12N 15/40 (2006.01)
Patent
CA 2365728
The present invention provides vaccine compositions of attenuated dengue-1 virus. More specifically, the attenuated virus is produced by serial passage in PDK cells. The invention also provides methods for stimulating the immune system of an individual to induce protection against dengue-1 virus by administration of attenuated dengue-1 virus.
La présente invention concerne des compositions de vaccin antiviral atténué du dengue de type 1. Plus spécifiquement, le virus atténué est produit par un passage en série dans des cellules PDK. L'invention concerne également des méthodes de stimulation du système immunitaire d'un individu afin d'induire une protection contre le virus du dengue de type 1 par administration du virus atténué du dengue de type 1.
Dubois Doria R.
Eckels Kenneth H.
Hoke Charles H.
Innis Bruce L.
Putnak Joseph R.
Gowling Lafleur Henderson Llp
Walter Reed Army Institute Of Research
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