Attenuated dengue-2 virus vaccine

Details Attenuated dengue-2 virus vaccine Attenuated dengue-2 virus vaccine

A - Human Necessities

61

K

A61K 39/12 (2006.01) C12N 7/04 (2006.01) C12N 7/08 (2006.01) C12N 15/40 (2006.01)

Patent

CA 2365411

The present invention provides vaccine compositions of attenuated dengue-2 virus. More specifically, the attenuated virus is produced by serial passage in PDK cells. The invention also provides methods for stimulating the immune system of an individual to induce protection against dengue-2 virus by administration of attenuated dengue-2 virus.

L'invention concerne des compositions de vaccin à base de virus dengue-2 atténué. Plus précisément, le virus atténué est produit par le passage sériel dans des cellules PDK. L'invention concerne également des procédés pour stimuler le système immunitaire d'un individu et le protéger contre le virus de dengue-2 par administration de virus de dengue-2 atténué.

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