Attenuated forms of bovine viral diarrhea virus

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/40 (2006.01) A61K 39/12 (2006.01) A61K 39/187 (2006.01) C07K 14/18 (2006.01) C07K 16/10 (2006.01) C12N 5/10 (2006.01) C12N 7/04 (2006.01) C12N 15/63 (2006.01) C12P 21/08 (2006.01)

Patent

CA 2287775

The present invention is directed to a method of producing attenuated forms of bovine viral diarrhea (BVD) virus by mutating the N pro protease gene. The invention includes the attenuated viruses made by this method, antibodies generated using these viruses, and vaccines that can be used for immunizing cattle.

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