Attenuated microorganisms for the treatment of infection

Details Attenuated microorganisms for the treatment of infection Attenuated microorganisms for the treatment of infection

A - Human Necessities

61

K

A61K 39/112 (2006.01) A61K 35/74 (2006.01) C07K 14/255 (2006.01) C12N 1/20 (2006.01) C12N 1/21 (2006.01) C12N 15/31 (2006.01)

Patent

CA 2372553

A <i>Salmonella</i> microorganism has an attenuating mutation which disrupts the expression of an apparatus gene located within the Spi2 pathogenicity island, and an auxotrophic mutation. The microorganism therefore has a double mutation which helps prevent reactivity of the microorganism while maintaining the effectiveness of the microorganism to elicit an immune response.

L'invention concerne un micro-organisme de Salmonelle présentant une mutation atténuante qui altère l'expression d'un gène d'appareil localisé à l'intérieur de l'îlot de pathogénie Spi2, et une mutation auxotrophe. Par conséquent, le micro-organisme présente une double mutation qui aide à empêcher la réactivité du micro-organisme, tandis que l'efficacité du micro-organisme à provoquer une réponse immunitaire est maintenue.

Affiliated with

Also associated with

Rating

Attenuated microorganisms for the treatment of infection does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Attenuated microorganisms for the treatment of infection, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Attenuated microorganisms for the treatment of infection will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1389581