Attenuation of opioid tolerance by inhibiting inducible...

Details Attenuation of opioid tolerance by inhibiting inducible... Attenuation of opioid tolerance by inhibiting inducible...

A - Human Necessities

61

K

A61K 31/55 (2006.01) A61K 31/195 (2006.01) A61K 31/198 (2006.01) A61K 31/40 (2006.01) A61K 31/41 (2006.01) A61K 31/485 (2006.01)

Patent

CA 2272941

Inducible nitric oxide (iNOS) inhibitors are used to prevent and/or reverse tolerance that is seen upon prolonged usage of opioids in the clinical management of moderate to severe pain.

On utilise des inhibiteurs de la monoxyde d'azote synthétase inductible dans le traitement de la douleur pour empêcher et/ou inverser la tolérance que l'on rencontre lors d'une prise prolongée d'opioïdes dans le traitement clinique de la douleur moyenne à aiguë.

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