Augmentation of intraluminal microvessel formation to...

Details Augmentation of intraluminal microvessel formation to... Augmentation of intraluminal microvessel formation to...

A - Human Necessities

61

K

A61K 38/19 (2006.01) A61F 2/06 (2006.01) A61K 35/14 (2006.01) A61K 38/18 (2006.01) A61M 25/09 (2006.01)

Patent

CA 2589523

Method, agent and apparatus for preparing a vessel, e.g., a human artery, for crossing of an occlusion situated therein. The method includes inducing angiogenesis in the occlusion, as by delivering an angiogenic agent to the occlusion site. Angiogenesis within the occlusion facilitates crossing by a guidewire during, e.g., angioplasty.

L~invention concerne un procédé, un agent et un appareil pour préparer un vaisseau, par ex., une artère humaine, pour franchir une occlusion située dans ce vaisseau. Le procédé consiste à induire une angiogénèse dans l'occlusion, sous forme d'administration d'un agent angiogénique au niveau du site de l'occlusion. L'angiogénèse à l'intérieur de l'occlusion facilite le passage d'un fil guide, par ex. au cours d'une angioplastie.

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