Aurore derivatives

Details Aurore derivatives Aurore derivatives

C - Chemistry, Metallurgy

07

D

260/304.7, 260/3

C07D 307/83 (2006.01) C07C 45/63 (2006.01) C07C 65/40 (2006.01) C07D 257/04 (2006.01) C07D 307/92 (2006.01) C07D 317/30 (2006.01) C07D 405/04 (2006.01)

Patent

CA 1202309

AURONE DERIVAT IVES ABSTRACT OF THE INVENTION Substituted aurones ot formula (I) : Image (I) wherein R1, R2, R3, R4, R5 and R6 are the same or different and can each represent hydrogen, halogen, C1-6 alkyl, C1-6 alkoxy, C3-8 cycloalkyl, optionally substituted phenyl, Cl 6 haloalkyl, amido, amino, cyano, hydroxy, nitro, C2-4 alkenyl, carboxyl, tetrazol-5-yl and -CH_CHCOOH; or wherein R1 and R2 taken together can represent a group of formula -CH-CH-CH-CH- provided that at least ono of R17 R2, R3, R4, R5 and R6 is carboxyl, tetrazol-5-yl or -CH=CICOOH; or a pharmaceutically-acceptable salt or ester thereof, are effective in the prophylactic chemotherapy of allergic conditions such as bronchial asthma.

335522

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