Autoantibodies which enhance the rate of a chemical reaction

C - Chemistry – Metallurgy – 12 – P

Patent

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167/139, 167/37,

C12P 21/00 (2006.01) A61K 35/16 (2006.01) A61K 39/395 (2006.01) C07K 14/575 (2006.01) C07K 16/06 (2006.01) C07K 16/26 (2006.01) C12N 9/00 (2006.01) C12N 9/48 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2015377

Autoantibodies which enhance the rate of a chemical reaction of a substrate, processes for their preparation, their use and compositions thereof are disclosed. In particular, an autoantibody capable of catalyzing the hydrolysis of the peptide bond between amino acid residues Thr7-Asp8, Arg14-Lys15, Gln16-Met17, Met17-Ala18, Ala18-Val19, Lys20-Lys21, Lys21-Tyr22 in the neurotransmitter vasoactive intestinal peptide (VIP) is disclosed.

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