Autoantibody inhibitors

Details Autoantibody inhibitors Autoantibody inhibitors

C - Chemistry, Metallurgy

07

K

C07K 14/705 (2006.01) A61K 39/395 (2006.01) A61P 25/28 (2006.01) C07K 16/28 (2006.01) G01N 33/53 (2006.01) G01N 33/564 (2006.01)

Patent

CA 2341240

The invention provides methods and compositions for inhibiting pathogenic binding of a pathogenic autoantibody to a myelin oligodendrocyte glycoprotein (MOG) autoantigen and screening for inhibitors of pathogenic binding of an autoantibody to a MOG autoantigen.

L'invention concerne des méthodes et compositions d'inhibition d'une liaison pathogène d'un auto-anticorps pathogène avec un auto-antigène de glycoprotéine oligodendrocyte de myéline (MOG) et de criblage d'inhibiteurs de liaison pathogène d'un auto-anticorps à un auto-antigène de MOG.

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