Autoimmune conditions and nadph oxidase defects

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/00 (2006.01) C12Q 1/26 (2006.01) C12Q 1/32 (2006.01) G01N 33/564 (2006.01)

Patent

CA 2483105

The invention relates to methods and materials involved in diagnosing and treating autoimmune conditions. In particular, the invention relates to methods and materials involved in diagnosing arthritis conditions that are accompanied by an NADPH oxidase deficiency, methods and materials involved in treating, preventing, or delaying the onset of arthritis conditions that are accompanied by an NADPH oxidase deficiency, and methods and materials involved in identifying agonists and antagonists of NADPH oxidase activity.

L'invention concerne des procédés et des matériaux pour le diagnostic et le traitement de maladies auto-immunes, et en particulier des procédés et des matériaux pour le diagnostic des affections arthritiques accompagnées par une déficience de NADPH oxydase, des procédés et des matériaux permettant de traiter, de prévenir ou de retarder l'apparition des affections arthritiques accompagnées par une déficience de NADPH oxydase, ainsi que des procédés et des matériaux pour l'identification d'agonistes et d'antagonistes vis-à-vis de l'activité de NADPH oxydase.

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