C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 9/00 (2006.01) A61K 31/7076 (2006.01) A61P 25/00 (2006.01) A61P 31/18 (2006.01) C07H 19/16 (2006.01) C07H 19/207 (2006.01) C12Q 1/25 (2006.01)
Patent
CA 2337710
Provided are compositions and methods useful for modulating the activity of autoinducer synthase catalysts. A method for identifying modulators of the autoinducers synthesis reaction is also provided. Such modulators are useful for controlling bacterial growth and can be used for therapeutic treatment of bacterial infections particularly in immunocompromised subjects. They are also useful in treating disease states associated with autoinducer synthesis and biofilm development.
L'invention concerne des compositions et des méthodes, permettant de moduler l'activité de catalyseurs de synthase auto-inductrice. L'invention concerne également une méthode permettant d'identifier des modulateurs de réaction de synthèse auto-indutrice. Ces modulateurs sont utiles pour réguler la croissance bactérienne, et peuvent être utilisés pour des traitements thérapeutiques d'infections bactériennes, en particulier chez des sujet immunodéprimés. Ils sont également utiles pour traiter des états de maladie associés à une synthèse auto-inductrice et à un développement de film biologique.
Cronan John E. Jr.
Greenberg E. Peter
Parsek Matthew R.
Plapp Bryce V.
Borden Ladner Gervais Llp
The University Of Iowa Research Foundation
LandOfFree
Autoinducer synthase modulating compounds and uses therefor does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Autoinducer synthase modulating compounds and uses therefor, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Autoinducer synthase modulating compounds and uses therefor will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1879346