Autologous bone graft material

A - Human Necessities – 61 – L

Patent

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Details

A61L 27/38 (2006.01) A61K 35/14 (2006.01) A61K 35/28 (2006.01) A61K 38/17 (2006.01) A61K 38/42 (2006.01) A61L 27/42 (2006.01) A61L 27/56 (2006.01) A61F 2/08 (2006.01) A61F 2/28 (2006.01) A61F 2/30 (2006.01)

Patent

CA 2423994

There is provided a musculoskeletogenic ("MSG") graft composite made from whole bone marrow aspirate ("BMA") having a native level of musculoskeletal progenitor cells ("MSPCs") and a native level of red blood cells ("RBCs"), comprising: a) a physiologic fraction of BMA comprising: i) MSPCs present in the physiologic fraction at a level greater than their native level in whole BMA, and ii) RBCs derived from BMA present in the physiologic fraction at a level less than their native level in whole BMA, and b) a porous sterile matrix having an average pore size of at least 20 µm.

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