Automated cytological specimen classification system and method

G - Physics – 01 – N

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G01N 33/574 (2006.01) C12Q 1/04 (2006.01) G01N 33/569 (2006.01) G01N 1/44 (2006.01) G01N 3/06 (2006.01) G06F 19/00 (2006.01)

Patent

CA 2182793

A semi-automated method of classifying a specimen for the presence of premalignant or malignant cells, including the steps of treating a specimen with immunochemical marker to provide a visual indication of cell proliferation, ranking individual objects in the specimen in an order according to the likelihood that each object has attributes consistent with a premalignant or malignant cell or cell cluster, selecting for display a set of said objects according to said ranking, and displaying images of said selected objects to facilitate review by an operator.

L'invention concerne un procédé semi-automatique pour la classification de prélèvements afin de déterminer la présence de cellules malignes ou pré-malignes. Ce procédé comprend les étapes consistant à traiter un prélèvement avec un marqueur immunochimique pour fournir une indication visuelle de la prolifération de cellules, à classer les objets individuels dans le prélèvement selon un ordre correspondant à la probabilité de chaque objet de posséder des attributs compatibles avec une cellule ou un groupe de cellules maligne(s) ou pré-maligne(s), à sélectionner, en vue de leur visualisation, un ensemble d'objets selon ce classement, et à afficher les images de ces objets pour faciliter leur examen par l'opérateur.

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