Automated method and apparatus for classification of cells...

G - Physics – 06 – K

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73/124, 73/168,

G06K 9/00 (2006.01) G01N 15/14 (2006.01)

Patent

CA 1135979

- 67 - AUTOMATED METHOD AND APPARATUS FOR CLASSIFICATION OF CELLS WITH APPLICATION TO THE DIAGNOSIS OF ANEMIA ABSTRACT A method and apparatus are disclosed for mea- suring characteristics of cells, such as red blood cells, and for analyzing parameters of the cell characteristics to define a patient's blood. These parameters may be com- pared for resemblance to predetermined reference charac- teristic values for a blood cell pathological condition such as a specific kind of anemia or for a normal blood. A report may be generated showing such resemblance to an anemia or to a normal blood. A report may generated showing parameters of a multivariate dispersion of distri- bution for a subpopulation of biconcave cells, an indica- tion of skewness of the distribution of the cells with regard to shape variations in central pallor size; the proportion of abnormal kinds of cells found, and close- ness of blood to several specific anemias. To expedite the system, a plurality of microprocessors are employed with one microprocessor controlling the imaging means and the summing of measured characteristics while one or more additional microprocessors are measuring characteristics and analyzing the digitized image signals. An improved method of measuring central pallor size is provided.

320757

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