G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/50 (2006.01) G01N 33/569 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2544706
The inventive method for automatically analysing a cellular sample consists (a) in colouring the cell nucleuses of a sample, (b) in obtaining at least one digital picture of the sample, and (c) in digitally analysing said image and is characterised in that the cell nucleus colouring stage (2) is embodied in the form of a DNA-non-specific colouring. In order to use the inventive method, said invention also relates to a method for selecting a culture medium, a method for measuring substance toxicity and to a method for measuring the cytopathological characteristics of a virus. A method for selecting pharmacological substances for treating excess weight and obesity diseases and a method for selecting substances for treating osteoporosis are also disclosed.
Le procédé d~analyse d~un échantillon cellulaire, comprend les étapes de : a) coloration des noyaux des cellules de l~échantillon ; b) acquisition d~au moins une image numérique de l~échantillon ; c) analyse numérique de ladite image caractérisé en ce que l~étape a) de coloration des noyaux des cellules est une coloration non spécifique à l~ADN. En application de ce procédé, l~invention propose aussi un procédé de sélection d~un milieu de culture, un procédé de mesure de la toxicité d~une substance et un procédé de mesure des caractéristiques cytopathologiques d~un virus. L~invention porte aussi sur un procédé de sélection de substances pharmacologiques intervenant dans les maladies du surpoids ou de l~obésité et un procédé de sélection de substances pharmacologiques intervenant dans l~ostéoporose.
Celogos
Robic
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