Automatic control system for improved electrophoresis

Details Automatic control system for improved electrophoresis Automatic control system for improved electrophoresis

G - Physics

05

B

G05B 13/02 (2006.01) B01D 57/02 (2006.01) G01N 27/447 (2006.01) G05B 15/00 (2006.01)

Patent

CA 2052037

61 PATENT Attorney Docket No. 2558-397 AUTOMATIC CONTROL SYSTEM FOR IMPROVED ELECTROPHORESIS ABSTRACT OF THE DISCLOSURE A system for improving the electrophoretic separation of macromolecules with the aid of a computer is described. The system maintains a knowledge base derived from calibration data obtained by separating macromolecules, in particular DNA, of known size under a variety of planned conditions chosen to optimize separations. The user enters the smallest and largest DNA sizes to be resolved. From this information, the system automatically sets the optimal Voltage Gradient, Angle, Initial Switch Time, Final Switch Time, Forward Voltage Gradient, and Reverse Voltage Gradient parameters, thereby increasing the resolution of electrophoresis.

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