Automatic electroporation optimization system

A - Human Necessities – 61 – N

Patent

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Details

A61N 1/30 (2006.01)

Patent

CA 2468750

Systems, methods and algorithms for automatically performing optimization of an electroporation system. A system according to the present invention typically includes a cuvette holding assembly (80) configured to hold a plurality of electroporation cuvettes (85), wherein each cuvette includes a first and second electrode, and a shocking chamber (75) configured to hold the cuvette holding assembly, the chamber having a commutator assembly configured to provide an electrical contact to the first electrode of each of the plurality of cuvettes in turn. The system also typically includes a control system communicably coupled to the shocking chamber, wherein the control system controls the commutator (100) to automatically contact the first electrode of each cuvette in an order and to provide a potential across the cuvette electrodes when contact is made.

Systèmes, procédés et algorithmes d'optimisation automatique pour système d'électroporation. Le système selon l'invention comprend généralement un ensemble support de cuvette (80) conçu pour recevoir une pluralité de cuvettes d'électroporation (85), comportant chacune une première et une seconde électrodes, et une chambre à chocs (75) conçue pour abriter l'ensemble support de cuvette, laquelle chambre est assortie d'un ensemble commutateur assurant tour à tour un contact électrique avec la première électrode de la pluralité de cuvettes. De plus, on trouve généralement un système de commande couplé à la chambre à chocs. Ce système commande au commutateur (100) d'établir automatiquement un contact avec la première électrode de chaque cuvette pour créer une différence de potentiel entre les électrodes de la cuvette au moment de l'établissement du contact.

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