C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/4365 (2006.01) A61K 31/437 (2006.01) A61K 31/4725 (2006.01) C07D 401/06 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01) C07D 495/04 (2006.01)
Patent
CA 2757415
The present invention relates to compounds according to formula (I) as autotaxin inhibitors and the use of such compounds for the treatment and/or prophylaxis of physiological and/or pathophysiological conditions, which are caused, mediat-ed and/or propagated by increased lysophosphatic acid levels and/or the activation of autotaxin, in particular of different cancers.
La présente invention porte sur des composés selon la formule (I) en tant qu'inhibiteurs de l'autotaxine et sur l'utilisation de tels composés pour le traitement et/ou la prévention d'états physiologiques et/ou physiopathologiques qui sont provoqués, médiés et/ou propagés par des taux accrus d'acide lysophosphatique et/ou par l'activation de l'autotaxine, en particulier de différents cancers.
Schiemann Kai
Schultz Melanie
Staehle Wolfgang
Fetherstonhaugh & Co.
Merck Patent Gmbh
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