A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/05 (2006.01) A61K 9/00 (2006.01) A61K 31/47 (2006.01) A61K 31/4709 (2006.01) A61P 43/00 (2006.01)
Patent
CA 2398792
A method of assisting ophthalmic operation and a method of relieving coagulativeness due to intraoperative bleeding by using (2R,4R)-4-methyl-1- [N2(RS)-3-methyl-1,2,3,4-tetrajydro-8-quinolinesulfonyl]-L-arginyl]-2- piperidine carboxylic acid, its hydrate or pharmaceutically acceptable salts thereof. These methods make it possible to easily control intraoperative bleeding, relieve the load upon patients and operators and lower the ratio of the occurrence of intraoperative iatrogenic retinal tear.
L'invention concerne une méthode permettant d'assister une opération ophtalmique ainsi qu'une méthode destinée à réguler la coagulation lors d'un saignement peropératoire au moyen d'un acide carboxylique de (2R,4R)-4-méthyl-1-[N?2¿(RS)-3-méthyl-1,2,3,4-tétrahydro-8-quinolinesulfonyl]-L-arginyl]-2-pipéridine, de son hydrate ou de sels pharmaceutiquement acceptables desdits composés. Ces méthodes permettent de réguler sans difficulté le saignement peropératoire, d'atténuer la charge pesant sur les patients et les chirurgiens et de réduire le risque de déchirure rétinienne iatrogénique peropératoire.
Maeno Takatoshi
Mano Tomiya
Fetherstonhaugh & Co.
Mitsubishi Pharma Corporation
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