Auxotrophic pseudomonas fluorescens bacteria

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/00 (2006.01) C12N 1/21 (2006.01) C12N 15/74 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2545610

The present invention provides an improved expression system for the production of recombinant polypeptides utilizing auxotrophic selectable markers. In addition, the present invention provides improved recombinant protein production in host cells through the improved regulation of expression.

L'invention concerne un système d'expression de protéine amélioré pour la production de polypeptides de recombinaison au moyen de marqueurs auxotrophes pouvant être sélectionnés. La présente invention porte également sur la production d'une protéine de recombinaison dans des cellules hôtes par l'amélioration de la régulation d'expression.

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