Avermectin derivatives

Details Avermectin derivatives Avermectin derivatives

C - Chemistry, Metallurgy

07

H

260/227

C07H 17/08 (2006.01) C07H 19/01 (2006.01)

Patent

CA 2006196

0075/DLR10 17790 TITLE OF THE INVENTION AVERMECTIN DERIVATIVES ABSTRACT OF THE DISCLOSURE Synthetically modified avermectin derivatives arc disclosed containing novel alkyl, and alkenyl substituents at position 25 and having additional substituents at positions 4'- and 4"- of the oleandrose structural part. The compounds are prepared from the known C-25 substituted avermectin derivatives by the appropriate chemical reactions at the 4'-, and 4"-positions. The new compounds are potent antiparasitic agents, in particular, the compounds are anthelmintic, insecticidal and acaricidal agents.

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