Avian polynucleotide vaccine formula

Details Avian polynucleotide vaccine formula Avian polynucleotide vaccine formula

A - Human Necessities

61

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A61K 48/00 (2006.01) A61K 31/70 (2006.01) A61K 39/12 (2006.01) A61K 39/145 (2006.01) A61K 39/155 (2006.01) A61K 39/17 (2006.01) A61K 39/21 (2006.01) A61K 39/215 (2006.01) A61K 39/245 (2006.01) A61K 39/255 (2006.01) A61K 39/295 (2006.01) C07K 14/01 (2006.01) C07K 14/03 (2006.01) C07K 14/055 (2006.01) C07K 14/08 (2006.01) C07K 14/11 (2006.01) C07K 14/115 (2006.01) C07K 14/125 (2006.01) C07K 14/15 (2006.01) C07K 14/165 (2006.01)

Patent

CA 2261343

An avian vaccine formula including at least three polynucleotide vaccine valencies that each include a plasmid containing an avian pathogen valency gene capable of being expressed in vivo in host cells. Said valencies are selected from the group which consists of Marek's disease virus, Newcastle disease virus, infectious bursal disease virus, infectious bronchitis virus and infectious anaemia virus. The plasmids include one or more genes per valency, and said genes are selected from the group which consists of gB and gD for Marek's disease virus, HN and F for Newcastle disease virus, VP2 for infectious bursal disease virus, S, M and N for infectious bronchitis virus and C + NS1 for infectious anaemia virus.

La formule de vaccin aviaire, comprend au moins trois valences de vaccin polynucléotidique comprenant chacune un plasmide intégrant, de manière à l'exprimer in vivo dans les cellules hôtes, un gène d'une valence de pathogène aviaire, ces valences étant choisies parmi le groupe consistant en virus de la maladie de Marek, virus de la maladie de Newcastle, virus de la maladie de Gumboro, virus de la bronchite infectieuse, virus de l'anémie infectieuse, les plasmides comprenant, pour chaque valence, un ou plusieurs des gènes choisis parmi le groupe consistant en gB et gD pour le virus de la maladie de Marek, MN et F pour le virus de la maladie de Newcastle, VP2 pour le virus de la maladie de Gumboro, S, M et N pour le virus de la bronchite infectieuse, C + NS1 pour le virus de l'anémie infectieuse.

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