Avicin-coated stents

Details Avicin-coated stents Avicin-coated stents

A - Human Necessities

61

L

A61L 31/16 (2006.01)

Patent

CA 2580847

The invention provides novel compositions and methods related to stents, such as coronary stents, comprising avicins, which are triterpene saponin compositions. In particular aspects of the invention, the avicins have growth- inhibiting properties and/or anti-inflammatory properties. In specific embodiments of the invention, the stent comprising the avicin reduces at least in part restenosis, such as that associated with stent procedures.

L'invention porte sur de nouvelles compositions et procédés relatives à des stents tels que des stents coronaires comprenant des avicines c.-à-d. des compositions de saponine triterpène. Selon des aspects particuliers de l'invention, lesdites avicines ont des propriétés inhibitrices de croissance et/ou des propriétés antiinflammatoires. Dans des exécutions spécifiques, le stent présentant des avicines réduit au moins partiellement la resténose associée aux procédures de mise en place des stents.

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