Axial chromatography columns and methods

B - Operations – Transporting – 01 – D

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B01D 15/22 (2006.01) G01N 30/60 (2006.01)

Patent

CA 2657720

The present invention relates to axial flow chromatography columns and methods for separating one or more analytes in a liquid by the use of such columns. The column comprises a first port for mobile phase and a transverse fluid distribution channel for distributing fluid uniformly throughout the packed bed. The first port comprises an inlet and an outlet having a passageway therebetween, the outlet having an asymmetric configuration relative to the fluid distribution channel.

La présente invention porte sur des colonnes de chromatographie à écoulement axial et sur des procédés pour séparer un ou plusieurs analytes dans un liquide par l'utilisation de telles colonnes. La colonne comprend un premier orifice pour phase mobile et un canal de distribution de fluide transversal pour distribuer un fluide de façon uniforme à travers la totalité du lit fixe. Le premier orifice comprend une entrée et une sortie ayant un passage entre celles-ci, la sortie ayant une configuration asymétrique par rapport au canal de distribution de fluide.

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