Aza-pyridopyrimidinone derivatives

Details Aza-pyridopyrimidinone derivatives Aza-pyridopyrimidinone derivatives

C - Chemistry, Metallurgy

07

D

C07D 475/02 (2006.01) A61K 31/519 (2006.01) A61P 3/06 (2006.01) C07D 487/04 (2006.01)

Patent

CA 2680775

The invention is concerned with novel aza-pyridopyrimidinone derivatives of formula (I) wherein R1, R2, R3, R4, R5, X1, X2, X3, Y, Z, m and n are as defined in the description and in the claims, as well as physiologically acceptable salts and esters thereof. These compounds are HM74A agonists and can be used as medicaments.

L'invention porte sur de nouveaux dérivés d'aza-pyridopyrimidinone de la formule (I), dans laquelle R1, R2, R3, R4, R5, X1, X2, X3, Y, Z, m et n sont tels que définis dans la description et les revendications. L'invention porte également sur sels physiologiquement acceptables et des esters de ces dérivés. Ces composés sont des agonistes de HM74A et peuvent être utilisés comme médicaments.

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