Azabicyclic compounds, preparation thereof and use of same...

C - Chemistry – Metallurgy – 07 – D

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C07D 471/08 (2006.01) A61K 31/439 (2006.01) A61P 31/04 (2006.01)

Patent

CA 2723020

The invention relates to compounds corresponding to the formula (I): in which R1 and R2 represent one a hydrogen and the other a fluorine or both a fluorine, in free form, in the form of zwitterions and of salts with pharmaceutically acceptable mineral or organic bases, preparation thereof and use of same as medicinal products that inhibit the action of ß-lactamases by pathogenic bacteria.

L' invention concerne les composés répondant à la formule ( I): dans laquelle R, et R2 représentent l'un un hydrogène et l'autre un fluor ou tous les deux un fluor, sous forme libre, de zwitterions et de sels avec les bases minérales ou organiques pharmaceutiquement acceptables, leur préparation et leur utilisation comme médicaments inhibiteurs de l'action des .beta.- lactamases par les bactéries pathogènes.

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