Azabicyclic derivatives and their therapeutic use

Details Azabicyclic derivatives and their therapeutic use Azabicyclic derivatives and their therapeutic use

C - Chemistry, Metallurgy

07

D

C07D 487/08 (2006.01) A61K 31/407 (2006.01) A61K 31/46 (2006.01) A61K 31/55 (2006.01) A61P 25/00 (2006.01) C07D 209/00 (2006.01) C07D 223/00 (2006.01) C07D 451/02 (2006.01)

Patent

CA 2417967

Pharmaceutical compositions incorporate compounds that are capable of affecting nicotinic cholinergic receptors. A wide variety of conditions and disorders, and particularly conditions and disorders associated with dysfunction of the central and autonomic nervous systems can be treated using pharmaceutical compositions incorporating compounds in which an aromatic ring is bridged with an ethylenic or acetylenic unit to an azabicyclic moiety.

L'invention concerne des compositions pharmaceutiques contenant des composés capables d'affecter des récepteurs cholinergiques nicotiniques. Une grande variété d'états et de troubles, et notamment, des états et des troubles liés au dysfonctionnement des systèmes nerveux autonome et central peuvent être traités au moyen des compositions pharmaceutiques contenant des composés dans lesquels un cycle aromatique est ponté par une unité éthylène ou acétylène avec un groupe fonctionnel azabicyclique.

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