Azabicyclic heterocycles as cannabinoid receptor modulators

Details Azabicyclic heterocycles as cannabinoid receptor modulators Azabicyclic heterocycles as cannabinoid receptor modulators

C - Chemistry, Metallurgy

07

D

C07D 487/04 (2006.01) A61K 31/5025 (2006.01) A61P 25/16 (2006.01) A61P 37/02 (2006.01) C07D 237/00 (2006.01) C07D 249/00 (2006.01)

Patent

CA 2550375

The present application describes compounds according to Formula I, pharmaceutical compositions comprising at least one compound according to Formula I and optionally one or more additional therapeutic agents and methods of treatment using the compounds according to Formula I both alone and in combination with one or more additional therapeutic agents. The compounds have the general Formula I. including all prodrugs, pharmaceutically acceptable salts and stereoisomers, R1, R2, R3, R4, R5, m and n are described herein.

La présente invention concerne des composés représentés par la formule (I), des compositions pharmaceutiques comprenant au moins un desdits composés et éventuellement un ou plusieurs agents thérapeutiques, ainsi que des méthodes de traitement au moyen des composés de formule (I) à la fois seuls et combinés avec un ou plusieurs agents thérapeutiques supplémentaires. Ces composés sont représentés par la formule (I), au même titre que tous les promédicaments, sels pharmaceutiquement acceptables et stéréoisomères de ces composés. Dans cette formule, R?1¿, R?2¿, R?3¿, R?4¿, R?5¿, m et n ont la signification qui leur est attribuée dans le descriptif.

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