C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/5025 (2006.01) A61P 25/16 (2006.01) A61P 37/02 (2006.01) C07D 237/00 (2006.01) C07D 249/00 (2006.01)
Patent
CA 2550435
The present application describes compounds according to Formula (I), pharmaceutical compositions comprising at least one compound according to Formula (I) and optionally one or more additional therapeutic agents and methods of treatment using the compounds according to Formula (I) both alone and in combination with one or more additional therapeutic agents. The compounds have the general Formula (I) including all prodrugs, pharmaceutically acceptable salts and stereoisomers, R1, R2, R3, R6, R7, m and n are described herein.
La présente application a trait à des composés de formule (I), à des compositions pharmaceutiques comportant au moins un composé de formule (I) et éventuellement un ou des agent(s) thérapeutique(s) et à des procédé de traitement mettant en oeuvre les composés de formule (I) seuls et en combinaison avec un ou des agent(s) thérapeutique(s). Les composés sont de formule générale (I) dans laquelle : R?1¿, R?2¿, R?3¿, R?6¿, R?7¿, m et n sont tels que définis dans la description, ainsi que tous les prodrogues, des sels et stéréoisomères pharmaceutiquement acceptables.
Ellsworth Bruce A.
Ewing William R.
Gerritz Samuel
Gu Zhengxiang
Huang Yanting
Bristol-Myers Squibb Company
Gowling Lafleur Henderson Llp
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