Azabicyclo compounds as calcium channel antagonists

Details Azabicyclo compounds as calcium channel antagonists Azabicyclo compounds as calcium channel antagonists

C - Chemistry, Metallurgy

07

D

C07D 487/08 (2006.01) A61K 31/395 (2006.01) C07D 471/08 (2006.01)

Patent

CA 2128536

2128536 9315080 PCTABS00024 Compounds of formula (I) in which p, q and r each independently represent an integer from 1 to 4; n is 0 to 6; m is 0 to 6; A is a bond, -CH=CH-, -C=C-, oxygen, sulphur or NR1; R1 is hydrogen, C1-8alkyl or phenylC1-4alkyl; and Ar is aryl or heteroaryl, each of which may be optionally substituted; and salts thereof are useful in medicine, in particular as calcium channel antagonists. Processes for preparing compounds (I) and pharmaceutical compositions containing them are also described.

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