Azabicyclo derivatives as muscarinic receptor antagonists

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 471/08 (2006.01) A61K 31/439 (2006.01) A61P 1/00 (2006.01) A61P 11/00 (2006.01) A61P 13/00 (2006.01)

Patent

CA 2521989

This invention generally relates to muscarinic receptor antagonists of formula (I) which are useful, among other uses for the treatment of various diseases of the respiratory, urinary and gastrointestinal systems mediated through muscarinic receptors. The invention also relates to pharmaceutical compositions containing the compounds of the present invention and the methods of treating the diseases mediated through muscarinic receptors.

La présente invention concerne généralement des antagonistes des récepteurs muscariniques de formule (I), lesquels sont utiles, entre autres usages, pour le traitement de diverses maladies des systèmes respiratoire, urinaire et gastro-intestinal médiées par les récepteurs muscariniques. L~invention concerne également des compositions pharmaceutiques contenant les composés décrits, ainsi que les méthodes pour traiter les maladies médiées par les récepteurs muscariniques.

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